Biochemical and structural investigations of Bothropstoxin-II, a myotoxic Asp49 phospholipase A(2) from Bothrops jararacussu venom
| Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
|---|---|
| Data(s) |
20/05/2014
20/05/2014
01/09/2008
|
| Resumo |
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Bothropstoxin-II a calcium-dependent enzyme from Bothrops jararacussu venom causes tissue damage and several haemostatic disorders including platelet aggregation. In order to elucidate the structural determinants of its multiple pharmacological activities, we have studied the effects of suramin on Bothropstoxin-II and present details concerning the mode of binding. |
| Formato |
1002-1008 |
| Identificador |
http://eurekaselect.com/83229/article Protein and Peptide Letters. Sharjah: Bentham Science Publ Ltd, v. 15, n. 9, p. 1002-1008, 2008. 0929-8665 http://hdl.handle.net/11449/22085 WOS:000259509800020 |
| Idioma(s) |
eng |
| Publicador |
Bentham Science Publ Ltd |
| Relação |
Protein and Peptide Letters |
| Direitos |
closedAccess |
| Palavras-Chave | #phospholipases A(2) #suramin #pharmacological activities #structural studies |
| Tipo |
info:eu-repo/semantics/article |
