Mapping the BDA20 Gene to BTAX
Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
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Data(s) |
20/05/2014
20/05/2014
01/01/2008
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Resumo |
The lipocalin family is a large group of proteins that exhibits great structural and functional variation both within and among species, including a significant number of animal-derived aeroallergens, such as the bovine BDA20 (major cow dander allergen). This protein is classified as an occupational allergen causing asthma and other work-related allergic disorders among dairy farmers. Using a somatic cell panel the BDA20 gene was assigned to the bovine X chromosome (BTAX) with a significant concordant value of 97% to the previously mapped reference marker MAF45. A radiation hybrid (RH) mapping approach confirmed the assignment of BDA20 to BTAX. Two-point LOD scores showed that BDA20 is linked to XBM451 with a LOD score of 22.1 for a 0 value of 0.03. |
Formato |
359-361 |
Identificador |
http://dx.doi.org/10.1159/000317186 Animal Genomics For Animal Health. Basel: Karger, v. 132, p. 359-361, 2008. 1424-6074 http://hdl.handle.net/11449/21590 10.1159/000317186 WOS:000264184200047 |
Idioma(s) |
eng |
Publicador |
Karger |
Relação |
Animal Genomics For Animal Health |
Direitos |
closedAccess |
Palavras-Chave | #BTAX #major cow dander allergen #X chromosome #BDA20 |
Tipo |
info:eu-repo/semantics/conferencePaper |