Rapid configuration analysis of the solenopsins


Autoria(s): Pianaro, Adriana; Fox, Eduardo G. P.; Bueno, Odair C.; Marsaioli, Anita J.
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

15/05/2012

Resumo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A protocol for rapid access to the relative and absolute configurations of the solenopsins, the venom alkaloids of fire ants (Solenopsis spp.), was developed based on chiral capillary gas chromatography. The synthesis of racemic mixtures of 2-methyl-6-alkylpiperidines and the isolation of natural (2R,6R)- and (2R,6S)-2-methyl-6-undecylpiperidines allowed for the standardization of the chromatographic method. Application of this protocol revealed the previously unknown natural occurrence of four stereoisomers of 2-methyl-6-undecylpiperidine in venom samples from workers and gynes of Solenopsis saevissima. (C) 2012 Elsevier Ltd. All rights reserved.

Formato

635-642

Identificador

http://dx.doi.org/10.1016/j.tetasy.2012.05.005

Tetrahedron-asymmetry. Oxford: Pergamon-Elsevier B.V. Ltd, v. 23, n. 9, p. 635-642, 2012.

0957-4166

http://hdl.handle.net/11449/19893

10.1016/j.tetasy.2012.05.005

WOS:000306252900002

Idioma(s)

eng

Publicador

Pergamon-Elsevier B.V. Ltd

Relação

Tetrahedron-asymmetry

Direitos

closedAccess

Tipo

info:eu-repo/semantics/article