Effect of propolis, some isolated compounds and its source plant on antibody production


Autoria(s): Sforcin, J. M.; Orsi, R. O.; Bankova, V
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

26/04/2005

Resumo

Propolis is a beehive product with a very complex chemical composition, widely used in folk medicine because of its several therapeutic activities. Its biological properties and chemical composition may vary according to the geographic location and to the different plant sources. The possible mechanism of action of propolis as well as of its active compounds has been the subject of researchers in recent years. In this work, first we reported the results of our study on the seasonal effect of the immunomodulatory action of propolis on antibody production in bovine serum albumin (BSA)-immunized rats. Then, we compared the effect of Brazilian and Bulgarian propolis, some isolated compounds and Baccharis extract on anti-BSA antibody levels. Based on the results, we conclude that propolis stimulates antibody production, independently of the season and geographic origin. Caffeic acid, quercetin and Baccharis extract had no effect on antibody production, although the importance of isolated compounds is well reported in other biological assays. Propolis action is a consequence of plant-derived products with synergic effects. while isolated compounds or extracts from its plant sources had no effect in this assay. (c) 2005 Elsevier B.V.. All rights reserved.

Formato

301-305

Identificador

http://dx.doi.org/10.1016/j.jep.2005.01.042

Journal of Ethnopharmacology. Clare: Elsevier Sci Ireland Ltd, v. 98, n. 3, p. 301-305, 2005.

0378-8741

http://hdl.handle.net/11449/18061

10.1016/j.jep.2005.01.042

WOS:000228688300011

Idioma(s)

eng

Publicador

Elsevier B.V.

Relação

Journal of Ethnopharmacology

Direitos

closedAccess

Palavras-Chave #propolis #antibody #caffeic acid #quercetin #Baccharis
Tipo

info:eu-repo/semantics/article