Effect of melatonin on the oxidative metabolism of colostrum phagocytes of diabetic women


Autoria(s): Calderon, Iracema de Mattos Paranhos; Morceli, G.; Hara, C.; Volpato, R.; Rudge, Marilza Vieira Cunha; Honorio-Franca, A.; Franca, E.; BenRafael, Z; Fauser, BCJM; Frydman, R
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

01/01/2011

Resumo

Aim: the aim of this study was verified the ability of melatonin hormone to modulate the oxidative metabolism of colostral phagocytes from diabetic mothers. Methods: based on 100g-OGTT and glucose profile analysis subjects were allocated into two groups: Non-diabetic (ND-10) and Diabetic (DM-8). Cells were separated by a Ficoll-Paque gradient and the oxidative metabolism was available thought superoxide release by colostrum phagocytes using the cytochrome C method. Results: melatonin hormone increased superoxide release by colostrum phagocytes of ND and decreased these release in colostrum phagocytes of DM mothers. Conclusion: the results suggest that the melatonin hormone can modulate the oxidative metabolism of phagocytes and an existence of relationship between control of glucose metabolism and melatonin action in colostrum phagocytes.

Formato

139-142

Identificador

http://www.monduzzieditore.it/shop/index.php?id_product=80&controller=product

14th World Congress on Controversies In Obstetrics, Gynecology & Infertility (cogi). Bologna: Monduzzi Editore S P A, p. 139-142, 2011.

http://hdl.handle.net/11449/12244

WOS:000313621800028

Idioma(s)

eng

Publicador

Monduzzi Editore S P A

Relação

14th World Congress on Controversies In Obstetrics, Gynecology & Infertility (cogi)

Direitos

closedAccess

Palavras-Chave #Colostrum #phagocytes #superoxide #melatonin #diabetes
Tipo

info:eu-repo/semantics/conferencePaper