Experimental myocardial hypertrophy induced by a minimally invasive ascending aorta coarctation


Autoria(s): Martins, A.S.; Aguilera, N.W.; Matsubara, B.B.; Bregagnollo, Edson Antônio
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

01/03/2001

Resumo

Ascending aorta coarctation was produced by a minimally invasive technique in rabbits. Animal mortality was 5%. Morphometric and hemodynamic parameters were evaluated. A parabiotically isolated heart model was used to assess the hemodynamic parameters. Left ventricular weight/body weight ratio and muscle area showed clear evidence of hypertrophy when compared to control. The hemodynamic changes in the isolated heart model suggested decreased diastolic and systolic function in the coarcted group. The present model produced hypertrophy with low mortality rates as a result of its less invasive nature.

Formato

413-415

Identificador

http://dx.doi.org/10.1590/S0100-879X2001000300017

Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 34, n. 3, p. 413-415, 2001.

0100-879X

http://hdl.handle.net/11449/11185

10.1590/S0100-879X2001000300017

S0100-879X2001000300017

S0100-879X2001000300017.pdf

Idioma(s)

eng

Publicador

Associação Brasileira de Divulgação Científica (ABRADIC)

Relação

Brazilian Journal of Medical and Biological Research

Direitos

openAccess

Palavras-Chave #ventricular hypertrophy #ventricular function #experimental model
Tipo

info:eu-repo/semantics/article