Cytotoxicity study of some Ti alloys used as biomaterial


Autoria(s): Donato, Tatiani A. G.; de Almeida, Luciano H.; Nogueira, Renata A.; Niemeyer, Terlize C.; Grandini, Carlos Roberto; Caram, Rubens; Schneider, Sandra G.; Santos, Arnaldo R.
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

05/05/2009

Resumo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

An implanted material is considered biocompatible, if adverse and uncontrollable reactions don't exist in the biological system. in this sense, biocompatibility tests made in the constituent materials are very important so that the implants have Success. The in vitro cytotoxicity tests represent the initial phase of the process, and Could be considered as a pre-selection of those materials. in vitro techniques using cell culture have become widely used in the evaluation of biomaterial cytotoxicity, which has contributed to their standardization and the substitution of in vivo tests. This paper shows a study of the in vitro cytotoxicity of two Ti based alloys, Ti-13Nb-13Zr and Ti-35Nb-7Zr-5Ta, in the as-received condition and after heat treated. The results show that the alloys presented no cytotoxic effects in the studied conditions. (C) 2008 Elsevier B.V. All rights reserved.

Formato

1365-1369

Identificador

http://dx.doi.org/10.1016/j.msec.2008.10.021

Materials Science & Engineering C-biomimetic and Supramolecular Systems. Amsterdam: Elsevier B.V., v. 29, n. 4, p. 1365-1369, 2009.

0928-4931

http://hdl.handle.net/11449/8498

10.1016/j.msec.2008.10.021

WOS:000269139900052

Idioma(s)

eng

Publicador

Elsevier B.V.

Relação

Materials Science & Engineering C-biomimetic and Supramolecular Systems

Direitos

closedAccess

Palavras-Chave #Biocompatibility #Ti alloys #Cytotoxicity #Cell culture
Tipo

info:eu-repo/semantics/article