Development and validation of a nonaqueous titration with perchloric acid to determine sparfloxacin in tablets


Autoria(s): Marona, HRN; Schapoval, EES
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

01/09/2001

Resumo

A simple, rapid and inexpensive method for the determination of sparfloxacin in tablets is described. The procedure is based on the use of volumetric dosage in a nonaqueous medium in glacial acetic acid with 0.1 M perchloric acid. The method validation yielded good results and included precision and accuracy. It was also found that the excipients in the commercial tablet preparation did not interfere with the assay. (C) 2001 Elsevier B.V. B.V. All rights reserved.

Formato

227-229

Identificador

http://dx.doi.org/10.1016/S0939-6411(01)00177-1

European Journal of Pharmaceutics and Biopharmaceutics. Amsterdam: Elsevier B.V., v. 52, n. 2, p. 227-229, 2001.

0939-6411

http://hdl.handle.net/11449/7608

10.1016/S0939-6411(01)00177-1

WOS:000171259000017

Idioma(s)

eng

Publicador

Elsevier B.V.

Relação

European Journal of Pharmaceutics and Biopharmaceutics

Direitos

closedAccess

Palavras-Chave #fluoroquinolone #nonaqueous titration #pharmaceutical analysis #sparfloxacin
Tipo

info:eu-repo/semantics/article