Synthesis of potentially bioactive PABA-related N-(aminoalkyl)lactamic amino acids and esters via selective SNAr reactions
| Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
|---|---|
| Data(s) |
20/05/2014
20/05/2014
01/01/2011
|
| Resumo |
Potentially bioactive N-(aminoalkyl)lactamic amino acids and esters were synthesized in satisfactory to good yields by SNAr reactions of aromatic acids with N-(3-aminopropyl)lactams followed by esterification with tertiary amino alcohols. The addition-elimination SNAr mechanism was confirmed by NMR and MS measurements. |
| Formato |
197-204 |
| Identificador |
http://dx.doi.org/10.1007/s00726-010-0634-z Amino Acids. New York: Springer, v. 40, n. 1, p. 197-204, 2011. 0939-4451 http://hdl.handle.net/11449/6863 10.1007/s00726-010-0634-z WOS:000285781000018 |
| Idioma(s) |
eng |
| Publicador |
Springer |
| Relação |
Amino Acids |
| Direitos |
closedAccess |
| Palavras-Chave | #PABA derivatives #Lactams #Potential bio-activity #SNAr reaction |
| Tipo |
info:eu-repo/semantics/article |
