Development of fluorescent and class selective HDAC Inhibitors
| Contribuinte(s) |
Pfeffer, Frederick |
|---|---|
| Data(s) |
01/02/2015
|
| Resumo |
The inhibition of HDAC enzymes has proven beneficial for the treatment of a variety of diseases including cancer. This thesis details the development of class selective and fluorescent HDAC inhibitors for cellular imaging. Increased HDAC and anticancer activities were observed, and the fluorescent inhibitors were readily visualised in live cells. |
| Identificador | |
| Idioma(s) |
eng |
| Publicador |
Deakin University, Faculty of Science, Engineering and Built Environment, School of Life and Environmental Sciences |
| Relação |
http://dro.deakin.edu.au/eserv/DU:30074274/fleming-agreement-2015.pdf http://dro.deakin.edu.au/eserv/DU:30074274/fleming-development-2015.pdf |
| Direitos |
The author |
| Palavras-Chave | #histone deacetylase (HDAC) enzymes #cancer therapy #fluorescent inhibitors #cellular imaging |
| Tipo |
Thesis |
