Locked nucleic acid aptamer based microfluidic devices for capturing tumor cells
Contribuinte(s) |
Kanwar Jagat Kanwar (nee Kaur), Rupinder |
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Data(s) |
01/07/2014
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Resumo |
Design and fabrication of novel microfluidic devices for sensitive and specific capture of circulating tumor cells using locked nucleic acid modified aptamers and antibodies targeting EpCAM/Nucleolin expression. These devices also allow re-usability, on-chip characterization of multiple markers and release of viable captured cells for further culture and in vitro characterization for cancer diagnosis, prognosis and therapeutic planning. |
Identificador | |
Idioma(s) |
eng |
Publicador |
Deakin University, Faculty of Health, School of Medicine |
Relação |
http://dro.deakin.edu.au/eserv/DU:30073093/maremanda-agreement-2014.pdf http://dro.deakin.edu.au/eserv/DU:30073093/maremanda-lockednucleic-2014A.pdf |
Direitos |
The Author. All Rights Reserved |
Palavras-Chave | #cancer diagnosis #cancer prognosis #cancer therapy #microfluidic devices #protein markers #biomarkers #locked nucleic acid |
Tipo |
Thesis |