Postchemotherapy and tumor-selective targeting with the La-specific DAB4 monoclonal antibody relates to apoptotic cell clearance


Autoria(s): Al-Ejeh,F; Staudacher,AH; Smyth,DR; Darby,JM; Denoyer,D; Tsopelas,C; Hicks,RJ; Brown,MP
Data(s)

01/05/2014

Resumo

Early identification of tumor responses to treatment is crucial for devising more effective and safer cancer treatments. No widely applicable, noninvasive method currently exists for specifically detecting tumor cell death after cytotoxic treatment and thus for predicting treatment outcomes.

Identificador

http://hdl.handle.net/10536/DRO/DU:30071642

Idioma(s)

eng

Publicador

Society of Nuclear Medicine

Relação

http://dro.deakin.edu.au/eserv/DU:30071642/denoyer-postchemotherapyand-2014.pdf

http://www.dx.doi.org/10.2967/jnumed.113.130559

http://www.ncbi.nlm.nih.gov/pubmed/24676755

Direitos

2014, Society of Nuclear Medicine

Palavras-Chave #APOMAB #DAB4 #La #apoptosis #chemotherapy #therapy response #Animals #Antibodies, Monoclonal, Murine-Derived #Antineoplastic Agents #Autoantigens #Binding, Competitive #Cell Proliferation #DNA Breaks, Double-Stranded #Female #Flow Cytometry #Humans #Jurkat Cells #Lymphoma #Male #Mice #Mice, Inbred BALB C #Mice, Inbred C57BL #Neoplasm Transplantation #Prostatic Neoplasms #Protein Binding #Radionuclide Imaging #Ribonucleoproteins #Thymocytes #Thymus Neoplasms #Treatment Outcome
Tipo

Journal Article