Granulocyte colony-stimulating factor receptor signalling via Janus kinase 2/signal transducer and activator of transcription 3 in ovarian cancer
Data(s) |
01/01/2014
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Resumo |
Ovarian cancer remains a major cause of cancer mortality in women, with only limited understanding of disease aetiology at the molecular level. Granulocyte colony-stimulating factor (G-CSF) is a key regulator of both normal and emergency haematopoiesis, and is used clinically to aid haematopoietic recovery following ablative therapies for a variety of solid tumours including ovarian cancer. |
Identificador | |
Idioma(s) |
eng |
Publicador |
Nature Publishing Group |
Relação |
http://dro.deakin.edu.au/eserv/DU:30067367/ward-granulocytecolony-2014.pdf http://www.dx.doi.org/10.1038/bjc.2013.673 http://www.ncbi.nlm.nih.gov/pubmed/24220695 |
Direitos |
2014, Nature Publishing Group |
Palavras-Chave | #cytokine #cytokine receptor #G-CSF #G-CSFR #JAK/STAT #ovarian cancer #STAT3 #Science & Technology #Life Sciences & Biomedicine #Oncology #G-CSF RECEPTOR #FACTOR-KAPPA-B #CELL-LINES #GENE-EXPRESSION #GROWTH-FACTOR #PHOSPHATIDYLINOSITOL 3-KINASE #STAT3 ACTIVATION #GASTRIC-CANCER #IN-VITRO #CARCINOMA |
Tipo |
Journal Article |