Evolution of the JAK-STAT pathway
Data(s) |
01/01/2013
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Resumo |
The JAK-STAT pathway represents a finely tuned orchestra capable of rapidly facilitating an exquisite symphony of responses from a complex array of extracellular signals. This review explores the evolution of the JAK-STAT pathway: the origins of the individual domains from which it is constructed, the formation of individual components from these basic building blocks, the assembly of the components into a functional pathway, and the subsequent reiteration of this basic template to fulfill a variety of roles downstream of cytokine receptors. |
Identificador | |
Idioma(s) |
eng |
Publicador |
Landes Bioscience |
Relação |
http://dro.deakin.edu.au/eserv/DU:30059495/ward-evolutionofthe-2013.pdf http://dx.doi.org/10.4161/jkst.22756 |
Direitos |
2013, Landes Bioscience |
Palavras-Chave | #JAK #Evolution #SHP #SOCS #STAT |
Tipo |
Journal Article |