X-ray crystallography : applications in the biotechnology research


Autoria(s): Sharma, Namita; Rana, Chandni; Verma, Madan Lal; Jana, Asim Kumar
Contribuinte(s)

[Unknown]

Data(s)

01/01/2010

Resumo

X-ray crystallography is essentially a form of very high resolution microscopy. It enables us to visualize protein structures at the atomic level and enhances our understanding of protein function. Specifically we can study how proteins interact with other molecules, how they undergo conformational changes, and how they perform catalysis in the case of enzymes. Armed with this information we can design novel drugs that target a particular protein, or rationally engineer an enzyme for a specific industrial process.

Identificador

http://hdl.handle.net/10536/DRO/DU:30054339

Idioma(s)

eng

Publicador

BEATS

Relação

http://dro.deakin.edu.au/eserv/DU:30054339/sharma-xray-post-2010.pdf

http://bmeindia.org/paper/BEATs2010_381.pdf

Palavras-Chave #Biomolecules #Crystals #Structure #drug designing
Tipo

Conference Paper