Phenyl-type and C1 stationary phases for environmentally friendlier chromatography


Autoria(s): Stevenson, Paul G.; Soliven, Arianne; Dennis, Gary R.; Shalliker, Ross A.
Data(s)

01/11/2009

Resumo

C1 and phenyl-type stationary phases were assessed in terms of their environmental impact on separations using as test solutes polycyclic aromatic hydrocarbons. Methanol (MeOH) and acetonitrile (ACN) mobile-phase gradients were employed. These stationary phases were examined to determine if different physical and chemical properties possessed by these surfaces decreased the organic solvent consumption, and yet maintained peak capacity. The cumulative energy demand (CED) was used to gauge the environmental impact of the separations. The separation of the polycyclic aromatic hydrocarbon test mixture using current methodologies (i.e. a C18/ACN combination) had a CED of 1.13 MJ-eq, and a peak capacity of 27 peaks (resolving 7 of 12 peak pairs with R<sub>s</sub>>1). In comparison, a butyl phenyl stationary phase with a methanol mobile phase had a peak capacity of 26, but with a CED of 0.670 MJ-eq. Monolithic columns containing C18 and C1 phases were also tested. A monolithic C18 column with MeOH had the lowest CED at 0.675 MJ-eq, a peak capacity of 28 peaks and good resolving power (resolving ten peak pairs with R<sub>s</sub>>1), suggesting that this is a viable option with respect to reducing environmental impact for these types of analyses.<br />

Identificador

http://hdl.handle.net/10536/DRO/DU:30047845

Idioma(s)

eng

Publicador

Wiley - V C H Verlag GmbH & Co. KGaA

Relação

http://dro.deakin.edu.au/eserv/DU:30047845/stevenson-phenyltype-2009.pdf

http://dx.doi.org/10.1002/jssc.200900479

Direitos

2009, WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Palavras-Chave #environmental impact #HPLC stationary phase #modified monoliths #phenyl type phases #polycyclic aromatic hydrocarbons
Tipo

Journal Article