A facile, protic ionic liquid route to N-substituted 5-hydroxy-4-methyl-3- oxoisoindoline-1-carboxamides


Autoria(s): Gordon, Christopher P; Byrne, Nolene; McCluskey, Adam
Data(s)

01/01/2010

Resumo

Treatment of highly decorated bicyclo[2.2.1]heptadienes with the protic ionic liquid, TfOH:TEA effected quantitative conversion to the corresponding N-substituted 5-hydroxy-4-methyl-3-oxoisoindoline-1-carboxamides. This approach provides rapid access important chemical space for the rapid development of highly functionalised oxoisoindoline and is highly substrate tolerant.<br />

Identificador

http://hdl.handle.net/10536/DRO/DU:30039448

Idioma(s)

eng

Publicador

Royal Society of Chemistry

Relação

http://dro.deakin.edu.au/eserv/DU:30039448/byrne-facile-2010.pdf

http://dx.doi.org/10.1039/B924835H

Direitos

2010, The Royal Society of Chemistry

Tipo

Journal Article