Is this D vitamin to worry about? Vitamin D insufficiency in an inpatient sample
Data(s) |
01/10/2008
|
---|---|
Resumo |
<b>Objective: </b>The aim of the present study was to investigate the relationship between reduced serum vitamin D levels and psychiatric illness.<br /><br /><b>Method:</b> This study was an audit of serum 25-hydroxyvitamin D (25-OHD) levels measured routinely in a sample of 53 inpatients in a private psychiatric clinic. These levels were compared with those of controls without psychiatric illness.<br /><br /><b>Results: </b>The median levels of serum 25-OHD were 43.0 nmol L<sup>−1</sup> (range 20–102 nmol L<sup>−1</sup>) in the patient population, 46.0 nmol L<sup>−1</sup> (range 20–102 nmol L<sup>−1</sup>) in female patients (n =33) and 41.5 nmol L<sup>−1</sup> (range 22–97 nmol L<sup>−1</sup>) in male patients (n =20). The proportion of vitamin D insufficiency (serum 25-OHD ≤50 nmol L<sup>−1</sup>) in this patient population was 58%. Furthermore, 11% had moderate deficiency (serum 25-OHD ≤25 nmol L<sup>−1</sup>). There was a 29% difference between mean levels in the patient population and control sample (geometric mean age- and season-adjusted levels: 46.4 nmol L<sup>−1</sup> (95% confidence interval (CI) =38.6–54.9 nmol L<sup>−1</sup>) vs 65.3 nmol L<sup>−1</sup> (95%CI =63.2–67.4 nmol L<sup>−1</sup>), p <0.001).<br /><br /><b>Conclusion: </b>Low levels of serum 25-OHD were found in this patient population. These data add to the literature suggesting an association between vitamin D insufficiency and psychiatric illness, and suggest that routine monitoring of vitamin D levels may be of benefit given the high yield of clinically relevant findings. |
Identificador | |
Idioma(s) |
eng |
Publicador |
Informa Healthcare |
Relação |
http://dro.deakin.edu.au/eserv/DU:30033151/jacka-isthisdvitamin-2008.pdf http://dx.doi.org/10.1080/00048670802345516 |
Direitos |
2008, Informa Healthcare |
Palavras-Chave | #depression #screening #vitamin D |
Tipo |
Journal Article |