Investigation of JAK/STAT signaling in human skeletal muscle
Data(s) |
01/01/2009
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Resumo |
Understanding muscle adaptation and repair is vital for preserving muscle loss with aging. Analysis of the inflammatory-responsive signalling pathway, JAK/STAT was performed. After intense exercise, the STAT3 pathway is highly activated, potentially by the pro-inflammatory regulator IL-6. This pathway is suppressed in older individuals, possible leading to altered inflammatory regulation. |
Identificador | |
Idioma(s) |
eng |
Publicador |
Deakin University, Faculty of Health, Medicine, Nursing and Behavioural Sciences, School of Exercise and Nutrition Sciences |
Palavras-Chave | #Striated muscle - Metabolism #Exercise - Physiological aspects |
Tipo |
Thesis |