Investigation of JAK/STAT signaling in human skeletal muscle


Autoria(s): Trenerry, Marissa K.
Data(s)

01/01/2009

Resumo

Understanding muscle adaptation and repair is vital for preserving muscle loss with aging. Analysis of the inflammatory-responsive signalling pathway, JAK/STAT was performed. After intense exercise, the STAT3 pathway is highly activated, potentially by the pro-inflammatory regulator IL-6. This pathway is suppressed in older individuals, possible leading to altered inflammatory regulation.

Identificador

http://hdl.handle.net/10536/DRO/DU:30030564

Idioma(s)

eng

Publicador

Deakin University, Faculty of Health, Medicine, Nursing and Behavioural Sciences, School of Exercise and Nutrition Sciences

Palavras-Chave #Striated muscle - Metabolism #Exercise - Physiological aspects
Tipo

Thesis