Mitrochondrial target discovery in diabetic skeletal muscle
| Data(s) |
01/01/2009
|
|---|---|
| Resumo |
This study identified the protein PARL (Presenilin-associated rhomboid like) as a potential mediator of the mitochondrial abnormalities that are observed in diabetic skeletal muscle. This was demonstrated by analysing PARL expression in an animal model of type 2 diabetes and by investigating the biological effects of genetic variation in the human PARL gene. |
| Identificador | |
| Idioma(s) |
eng |
| Publicador |
Deakin University, Faculty of Health, Medicine, Nursing and Behavioural Sciences, School of Medicine |
| Palavras-Chave | #Striated muscle - Genetic aspects #Gene expression #Non-insulin-dependent diabetes - Genetic aspects #Mitochondria - Genetic aspects #Mitochondrial pathology |
| Tipo |
Thesis |
