Synthesis of a novel pyrrole oxazole analogue of the insecticide pirate
Data(s) |
01/01/2004
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Resumo |
The pyrrole oxazole 4 is a novel analogue of the broad-spectrum insecticide and miticide pirate 2. The expedient synthesis of pyrrole oxazole 4 in six steps from pyrrole is reported using a synthetic route that could have potential for the solution-phase combinatorial synthesis of analogues. Preliminary biological evaluation of the protected pyrrole oxazole 4 (LD<sub>50</sub> 1.13 μg mL<sup>–1</sup>) and the deprotected pyrrole oxazole 5 (LD<sub>50</sub> 1.06 μg mL<sup>–1</sup>) for potential cytotoxicity was carried out.<br /> |
Identificador | |
Idioma(s) |
eng |
Publicador |
CSIRO Publishing |
Relação |
http://dro.deakin.edu.au/eserv/DU:30028587/henderson-synthesisofanovel-2004.pdf http://dx.doi.org/10.1071/CH03184 |
Direitos |
2004, CSIRO |
Tipo |
Journal Article |