Characterisation and comparison of bovine RNA polymerase III promoters for RNA interference


Autoria(s): Lambeth, Luke Simon.
Data(s)

01/01/2006

Resumo

The characterisation of novel bovine RNA polymerase III promoters for the expression of short hairpin RNAs for gene silencing resulted in the identification of a highly efficient promoter sequence. The replication of bovine viral diarrhea virus was them suppressed using short hairpin RNAs expressed form this promoter in vitro.

Identificador

http://hdl.handle.net/10536/DRO/DU:30027160

Idioma(s)

eng

Publicador

Deakin University, Faculty of Science and Technology, School of Life and Environmental Sciences

Palavras-Chave #Gene silencing #RNA polymerases #Virus diseases - Genetic aspects #Cattle - Diseases - Genetic aspects
Tipo

Thesis