Identification of proteins that interact with the copper transporter ATP7B
Data(s) |
01/01/2006
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Resumo |
In this study proteins were identified that interact with the key liver enzyme, ATP7B that is affected in the copper toxicity disorder Wilson disease. Detailed characterisation of the interaction with glutaredoxin and dynactin subunit p62 contributes significantly towards our understanding of the mechanisms that regulate copper balance in the body. |
Identificador | |
Idioma(s) |
eng |
Publicador |
Deakin University, Faculty of Science and Technology, School of Life and Environmental Sciences |
Palavras-Chave | #Copper proteins #Copper enzymes #Homeostasis #Metabolism, Inborn errors of #Liver - Diseases |
Tipo |
Thesis |