Long-term effects of a reduced fat diet intervention on cardiovascular disease risk factors in individuals with glucose intolerance
Data(s) |
01/02/2004
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Resumo |
The long-term effects on cardiovascular disease risk factors of a reduced fat (RF), ad libitum diet were compared with usual diet (control, CD) in glucose intolerance individuals.<br /><br />Participants were 136 adults aged ≥40 years with ‘glucose intolerance’ (2 h blood glucose 7–11.0 mmol/l) detected at a Diabetes Survey who completed at 1 year intervention study of reduced fat, ad libitum diet versus usual diet. They were re-assessed at 2, 3 and 5 years. Main outcome measures were blood pressure, serum concentrations of total cholesterol, HDL and LDL cholesterol, total cholesterol:HDL ratio, triglycerides and body weight.<br /><br />The reduced fat diet lowered total cholesterol (P<0.01), LDL cholesterol (P≤0.05), total cholesterol:HDL ratio (P≤0.05), body weight (P<0.01) and systolic blood pressure (P≤0.05) initially and diastolic blood pressure (P<0.01) long-term. No significant changes occurred in HDL cholesterol or triglycerides. In the more compliant 50% of the intervention group, systolic and diastolic blood pressure levels and body weight were lower at 1, 2 and 3 years (P<0.05).<br /><br />It was concluded that a reduced fat ad libitum diet has short-term benefits for cholesterol, body weight and systolic blood pressure and long-term benefits for diastolic blood pressure without significantly effecting HDL cholesterol and triglycerides despite participants regaining their lost weight.<br /> |
Identificador | |
Idioma(s) |
eng |
Publicador |
Elsevier Ireland Ltd |
Relação |
http://dro.deakin.edu.au/eserv/DU:30008675/n20040269.pdf http://dx.doi.org/10.1016/j.diabres.2003.09.001 |
Direitos |
2003, Elsevier Ireland |
Palavras-Chave | #Glucose intolerance #Reduced fat diet #Cardiovascular disease risk factors #Cholesterol #Blood pressure |
Tipo |
Journal Article |