Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkâ


Autoria(s): Yuan, Minsheng; Konstantopoulos, Nicky; Lee, Jongsoon; Hansen, Lone; Li, Zhi-Wei; Karin, Michael; Shoelson, Steven E.
Data(s)

31/08/2001

Resumo

Focuses on the reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IkB kinase beta (IKKbeta) Definition of insulin resistance; Recognition of the IKKbeta pathway as the target for insulin sensitization; Impact of the increase of IKKbeta activity on obese rodents.<br />

Identificador

http://hdl.handle.net/10536/DRO/DU:30006578

Idioma(s)

eng

Publicador

American Association for the Advancement of Science

Relação

http://dro.deakin.edu.au/eserv/DU:30006578/konstantopoulos-reversalof-2001.pdf

http://dx.doi.org/10.1126/science.1061620

Direitos

2001, American Association for the Advancement of Science

Tipo

Journal Article