Photochemical N-demethylation of Alkaloids
| Data(s) |
01/02/2001
|
|---|---|
| Resumo |
Certain alkaloids were observed to undergo N-demethylation processes under photochemical conditions. Tropine, acetyltropine, tropinone, and atropine were cleanly N-demethylated upon treatment with tetraphenylporphin, oxygen, and light. Dextromethorphan also underwent a N-demethylation reaction, but reacted further to afford an imine. In contrast, 14-acyloxycodeinones underwent a photochemically induced tandem N-demethylation–acyl migration.<br /> |
| Identificador | |
| Idioma(s) |
eng |
| Publicador |
Pergamon |
| Relação |
http://dro.deakin.edu.au/eserv/DU:30001419/scammells-photochemical-2001.pdf http://dx.doi.org/10.1016/S0960-894X(00)00690-9 |
| Direitos |
2001, Elsevier Science Ltd. |
| Tipo |
Journal Article |
