Determination of Minoxidil by Bleaching the Permanganate Carrier Solution in a Flow-Based Spectrophotometric System
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
20/10/2012
20/10/2012
2011
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| Resumo |
The determination of minoxidil (MX) with potassium permanganate as a carrier in a flow injection method is described. The detection at 550nm was linear from 1.0x10-5 to 5.0x10-4mol L-1. The limit of detection (3 sigma/slope) was 8.92x10-6mol L-1, with an analytical frequency of 32h-1. The proposed method was applied to commercial samples, with recoveries from 104.7 to 106.4%. Comparison with the HPLC procedure reveled relative errors from 0.48 to 1.4%, and the results agreed within a 95% confidence level. Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) FAPESP[08/03537-7] Universidade de São Paulo - Programa PROCONTES/USP Universidade de São Paulo - Programa PROCONTES/USP |
| Identificador |
ANALYTICAL LETTERS, v.44, n.1/Mar, p.349-359, 2011 0003-2719 http://producao.usp.br/handle/BDPI/31792 10.1080/00032719.2010.500778 |
| Idioma(s) |
eng |
| Publicador |
TAYLOR & FRANCIS INC |
| Relação |
Analytical Letters |
| Direitos |
restrictedAccess Copyright TAYLOR & FRANCIS INC |
| Palavras-Chave | #Antihypertensive drug analysis #Flow injection #Minoxidil #Permanganate bleaching #Spectrophotometric detection #ALOPECIA-AREATA #DRUGS #HPLC #Chemistry, Analytical |
| Tipo |
article original article publishedVersion |
