Synthesis and application of chiral beta-amino disulfides as ligands for the enantioselective addition of diethylzinc to aldehydes
Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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Data(s) |
20/10/2012
20/10/2012
2008
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Resumo |
A new class of chiral beta-amino disulfides was synthesized from readily available and inexpensive starting materials by a straightforward method and their abilities as ligands were examined in the enantioselective addition of diethylzinc to aldehydes. Enantiomeric excesses of up to 99% have been obtained using 0.5 mol % of the chiral catalysts. |
Identificador |
CHIRALITY, v.20, n.7, p.839-845, 2008 0899-0042 http://producao.usp.br/handle/BDPI/31556 10.1002/chir.20554 |
Idioma(s) |
eng |
Publicador |
WILEY-LISS |
Relação |
Chirality |
Direitos |
restrictedAccess Copyright WILEY-LISS |
Palavras-Chave | #asymmetric catalysis #chiral ligands #thiols #sulfur #zinc #ASYMMETRIC ALLYLIC ALKYLATION #ORGANOZINC REAGENTS #CARBONYL-COMPOUNDS #ARYL TRANSFER #ORGANOSELENIUM COMPOUNDS #ALKYLLITHIUM REAGENTS #PROPARGYLIC ALCOHOLS #EPHEDRA ALKALOIDS #SULFIDE LIGANDS #BORONIC ACIDS #Chemistry, Medicinal #Chemistry, Analytical #Chemistry, Organic #Pharmacology & Pharmacy |
Tipo |
article original article publishedVersion |