Room Temperature, Metal-Free Synthesis of Diaryl Ethers with Use of Diaryliodonium Salts
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
20/10/2012
20/10/2012
2011
|
| Resumo |
A fast, high-yielding synthesis of diaryl ethers with use of mild and metal-free conditions has been developed. The scope includes bulky ortho-substituted diaryl ethers, which are difficult to obtain by metal-catalyzed protocols. Halo-substituents, racemization-prone amino acid derivatives, and heteroaromatics are also tolerated. The methodology is expected to be of high utility in the synthesis of complex molecules and in the pharmaceutical industry. Swedish Research Council Swedish Research Council Swedish Foundation for International Cooperation in Research and Higher Education (STINT) Swedish Foundation for International Cooperation in Research and Higher Education (STINT) CNPq Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) |
| Identificador |
ORGANIC LETTERS, v.13, n.6, p.1552-1555, 2011 1523-7060 http://producao.usp.br/handle/BDPI/31382 10.1021/ol200265t |
| Idioma(s) |
eng |
| Publicador |
AMER CHEMICAL SOC |
| Relação |
Organic Letters |
| Direitos |
restrictedAccess Copyright AMER CHEMICAL SOC |
| Palavras-Chave | #ONE-POT SYNTHESIS #POLYBROMINATED DIPHENYL ETHERS #COUPLING REACTIONS #ARYLBORONIC ACIDS #NATURAL-PRODUCTS #ARYL IODIDES #ARYLATION #PHENOLS #IODINE #BOND #Chemistry, Organic |
| Tipo |
article original article publishedVersion |
