Caldensinic acid, a prenylated benzoic acid from Piper caldense


Autoria(s): FREITAS, Giovana C.; KITAMURA, Rodrigo O. Saga; LAGO, Joao Henrique G.; YOUNG, Maria Claudia M.; GUIMARAES, Elsie F.; KATO, Massuo J.
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

20/10/2012

20/10/2012

2009

Resumo

The CH(2)Cl(2) and MeOH extracts from leaves of Piper caldense were subjected to chromatographic separation procedures to afford the new prenylated benzoic acid, caldensinic acid (3-[(2`E,6`E,10`E)-11`-carboxy-3`,7`,15`-trimethylhexadeca-2`,6`,10`,14`-tetraenyl]-4,5-dihydroxybenzoic acid) whose structure was determined by spectral analysis, mainly NMR ((1)H, (13)C, HSQC, HMBC) and ESI-MS. The natural compound and derivatives displayed antifungal activity against the phytopathogenic fungi Cladosporium cladosporioides and C. sphaerospermum by direct bioautography. (C) 2009 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

FAPESP

MackPesquisa

MackPesquisa

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

CNPq

Identificador

PHYTOCHEMISTRY LETTERS, v.2, n.3, p.119-122, 2009

1874-3900

http://producao.usp.br/handle/BDPI/31164

10.1016/j.phytol.2009.03.006

http://dx.doi.org/10.1016/j.phytol.2009.03.006

Idioma(s)

eng

Publicador

ELSEVIER SCIENCE BV

Relação

Phytochemistry Letters

Direitos

restrictedAccess

Copyright ELSEVIER SCIENCE BV

Palavras-Chave #Piper caldense #Piperaceae #Prenylated benzoic acid #Caldensinic acid #Antifungal activity #Biochemistry & Molecular Biology #Plant Sciences
Tipo

article

original article

publishedVersion