On the use of 2,1,3-benzothiadiazole derivatives as selective live cell fluorescence imaging probes


Autoria(s): OLIVEIRA, Felipe F. D.; SANTOS, Diego C. B. D.; LAPIS, Alexandre A. M.; CORREA, Jose R.; GOMES, Alexandre F.; GOZZO, Fabio C.; MOREIRA JR., Paulo F.; OLIVEIRA, Virginia C. de; QUINA, Frank H.; D. NETO, Brenno A.
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

20/10/2012

20/10/2012

2010

Resumo

Newly designed 2,1,3-benzothiadiazole-containing fluorescent probes with four excited state intramolecular proton transfer (ESIPT) sites were successfully tested in live cell-imaging assays using a confluent monolayer of human stem-cells (tissue). All tested dyes were compared with the commercially available DAPI and gave far better results. (c) 2010 Elsevier Ltd. All rights reserved.

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

CAPES

CNPq

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Financiadora de Estudos e Projetos (FINEP)

FINEP

Finatec

Finatec

FAPESP

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

FAPDF

FAPDF

Identificador

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.20, n.20, p.6001-6007, 2010

0960-894X

http://producao.usp.br/handle/BDPI/31024

10.1016/j.bmcl.2010.08.073

http://dx.doi.org/10.1016/j.bmcl.2010.08.073

Idioma(s)

eng

Publicador

PERGAMON-ELSEVIER SCIENCE LTD

Relação

Bioorganic & Medicinal Chemistry Letters

Direitos

restrictedAccess

Copyright PERGAMON-ELSEVIER SCIENCE LTD

Palavras-Chave #Synthesis #Benzothiadiazole #ESIPT #Live cell-imaging #Stem-cells #INTRAMOLECULAR PROTON-TRANSFER #SENSITIVE FLUOROPHORES #TRANSFER ESIPT #DNA #SOLVENT #DESIGN #Chemistry, Medicinal #Chemistry, Organic
Tipo

article

original article

publishedVersion