Ultrastructural Aspects of Female Aging Wistar Rat Epithelium Tongue: A HRSEM and TEM Study


Autoria(s): LOPES, Marilia Gabriela de Oliveira; WATANABE, Ii-sei; SOARES, Luis Eduardo Silva; SILVA, Newton Soares da; SILVA, Marcelo Cavenaghi Pereira da
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

20/10/2012

20/10/2012

2009

Resumo

Background: There is general consensus that the effects of intrinsic aging on the oral mucosa are relatively small, though potentially important to understanding the pathologies present in the aged animals. Objective: In this paper, the development of dorsal surface of rat tongue was examined using transmission electron microscopy (TEM) and high-resolution scanning electron microscopy (HRSEM) in order to understand the age-related structural and ultrastructural changes experimentally. Methods: In this study, we used female rats 75 and 720 days old (adult and aging). Tissues of rat tongue were prepared and the specimens submitted to HRSEM and TEM techniques. Results: The analysis of HRSEM and TEM demonstrated that the same characteristic keratinous epithelium was found in aging animals, however with some modifications. Conclusion: We agree that there are obvious changes in the oral mucosa with aging and these modifications can be observed starting from the ultrastructural aspects. Copyright (C) 2009 S. Karger AG, Basel

Identificador

GERONTOLOGY, v.55, n.4, p.442-448, 2009

0304-324X

http://producao.usp.br/handle/BDPI/28585

10.1159/000216829

http://dx.doi.org/10.1159/000216829

Idioma(s)

eng

Publicador

KARGER

Relação

Gerontology

Direitos

restrictedAccess

Copyright KARGER

Palavras-Chave #Oral mucosa #Tongue #High-resolution scanning electron microscopy #Transmission electron microscopy #ORAL-MUCOSA #ELECTRON-MICROSCOPY #CELL-DEATH #AGE #DEGENERATION #MITOCHONDRIA #DAMAGE #Geriatrics & Gerontology
Tipo

article

original article

publishedVersion