Propagation of a Brazilian isolate of Anaplasma marginale with appendage in a tick cell line (BME26) derived from Rhipicephalus (Boophilus) microplus

Anaplasma marginale is a tick-borne pathogen of cattle responsible for the disease anaplasmosis. Data suggest that Rhipicephalus (Boophilus) microplus and R. annulatus may be the major tick vectors of A. marginale in tropical and subtropical regions of the world. In this work we demonstrated the first infection and propagation of a Brazilian isolate of A. marginale (UFMG1) in the BME26 cell line derived originally from embryos of R. (Boophilus) microplus. The establishment of A. marginale infection in a cell line derived from R. (Boophilus) microplus is relevant for studying the A. marginale/tick interface. (C) 2008 Elsevier B.V. All rights reserved.

FAPESP (Fundacao de Amparo a Pesquisa do Estado de Sao Paulo, Brazil)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

CNPq (Conselho Nacional de Desenvolvimento Cientifico e Tecnologico, Brazil)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Consejeria de Educacion y Ciencia, JCCM, Spain[PA106-0046-5285]

Consejeria de Educacion y Ciencia, JCCM, Spain

Integrated Consortium on Ticks and Tick-borne Diseases (ICTTD-3)

Integrated Consortium on Ticks and Tick-borne Diseases (ICTTD-3)

European Union[510561]

European Union