Reduced cytokine production by glycogen-elicited peritoneal cells from diabetic rats
Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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Data(s) |
20/10/2012
20/10/2012
2008
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Resumo |
IL-1 beta, TNF-alpha, cytokine-induced neutrophil chemoattractant-2 alpha/beta, and IL-10 measurements were performed in elicited peritoneal cells from control, diabetic, and insulin-treated diabetic rats. Production/liberation of these cytokines was decreased in elicited peritoneal cells from diabetic rats. These changes were abolished by insulin treatment of diabetic rats. The alterations observed might be involved in the impaired inflammatory response and high occurrence of apoptosis observed in neutrophils under diabetic states. |
Identificador |
SHOCK, v.30, n.3, p.308-310, 2008 1073-2322 http://producao.usp.br/handle/BDPI/27940 10.1097/SHK.0b013e318164e834 |
Idioma(s) |
eng |
Publicador |
LIPPINCOTT WILLIAMS & WILKINS |
Relação |
Shock |
Direitos |
restrictedAccess Copyright LIPPINCOTT WILLIAMS & WILKINS |
Palavras-Chave | #leukocytes #diabetes #IL-1 beta #TNF-alpha #IL-10 #CINC-2 alpha/beta #TUMOR-NECROSIS-FACTOR #HUMAN POLYMORPHONUCLEAR LEUKOCYTES #HUMAN NEUTROPHILS #FACTOR-ALPHA #RECEPTOR ANTAGONIST #TNF-ALPHA #HIGH-RISK #APOPTOSIS #IL-10 #INTERLEUKIN-10 #Critical Care Medicine #Hematology #Surgery #Peripheral Vascular Disease |
Tipo |
article original article publishedVersion |