Reduced cytokine production by glycogen-elicited peritoneal cells from diabetic rats


Autoria(s): ALBA-LOUREIRO, Tatiana Carolina; PITHON-CURI, Tania Cristina; Curi, Rui
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

20/10/2012

20/10/2012

2008

Resumo

IL-1 beta, TNF-alpha, cytokine-induced neutrophil chemoattractant-2 alpha/beta, and IL-10 measurements were performed in elicited peritoneal cells from control, diabetic, and insulin-treated diabetic rats. Production/liberation of these cytokines was decreased in elicited peritoneal cells from diabetic rats. These changes were abolished by insulin treatment of diabetic rats. The alterations observed might be involved in the impaired inflammatory response and high occurrence of apoptosis observed in neutrophils under diabetic states.

Identificador

SHOCK, v.30, n.3, p.308-310, 2008

1073-2322

http://producao.usp.br/handle/BDPI/27940

10.1097/SHK.0b013e318164e834

http://dx.doi.org/10.1097/SHK.0b013e318164e834

Idioma(s)

eng

Publicador

LIPPINCOTT WILLIAMS & WILKINS

Relação

Shock

Direitos

restrictedAccess

Copyright LIPPINCOTT WILLIAMS & WILKINS

Palavras-Chave #leukocytes #diabetes #IL-1 beta #TNF-alpha #IL-10 #CINC-2 alpha/beta #TUMOR-NECROSIS-FACTOR #HUMAN POLYMORPHONUCLEAR LEUKOCYTES #HUMAN NEUTROPHILS #FACTOR-ALPHA #RECEPTOR ANTAGONIST #TNF-ALPHA #HIGH-RISK #APOPTOSIS #IL-10 #INTERLEUKIN-10 #Critical Care Medicine #Hematology #Surgery #Peripheral Vascular Disease
Tipo

article

original article

publishedVersion