Self-assembly of the anti-fungal polyene amphotericin B into giant helically-twisted nanotapes


Autoria(s): Hamley, Ian William; Kirkham, Steven; Kowalczyk, Radoslaw M.; Castelletto, Valeria; Reza, Mehedi; Ruokolainen, Janne
Data(s)

20/10/2015

Resumo

The amphiphilic polyene amphotericin B, a powerful treatment for systemic fungal infections, is shown to exhibit a critical aggregation concentration, and to form giant helically-twisted nanostructures via self-assembly in basic aqueous solution.

Formato

text

Identificador

http://centaur.reading.ac.uk/48786/1/c5cc08224b.pdf

Hamley, I. W. <http://centaur.reading.ac.uk/view/creators/90000472.html>, Kirkham, S., Kowalczyk, R. M. <http://centaur.reading.ac.uk/view/creators/90005581.html>, Castelletto, V. <http://centaur.reading.ac.uk/view/creators/90000493.html>, Reza, M. and Ruokolainen, J. (2015) Self-assembly of the anti-fungal polyene amphotericin B into giant helically-twisted nanotapes. Chemical Communications, 51 (100). pp. 17680-17683. ISSN 1359-7345 doi: 10.1039/C5CC08224B <http://dx.doi.org/10.1039/C5CC08224B>

Idioma(s)

en

Publicador

The Royal Society of Chemistry

Relação

http://centaur.reading.ac.uk/48786/

creatorInternal Hamley, Ian William

creatorInternal Kowalczyk, Radoslaw M.

creatorInternal Castelletto, Valeria

http://dx.doi.org/10.1039/C5CC08224B

10.1039/C5CC08224B

Direitos

cc_by

Tipo

Article

PeerReviewed