Molecular basis of platelet activation by an alphaIIbbeta3-CHAMPS peptide.
| Data(s) |
01/02/2009
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|---|---|
| Resumo |
The present study demonstrates that the alphaIIb-CHAMPS peptide induces platelet activation through integrin alphaIIbbeta3-dependent and independent pathways with the former mediating tyrosine phosphorylation of FcR gamma-chain and Syk. The use of the alphaIIb-CHAMPS peptide to study integrin alphaIIbbeta3 function is compromised by non-integrin-mediated effects. |
| Formato |
text |
| Identificador |
http://centaur.reading.ac.uk/44579/1/Grygielska%20et%20al%20JTH%202009.pdf Grygielska, B., Hughes, C. E. <http://centaur.reading.ac.uk/view/creators/90006851.html> and Watson, S. P. (2009) Molecular basis of platelet activation by an alphaIIbbeta3-CHAMPS peptide. Journal of thrombosis and haemostasis : JTH, 7 (2). pp. 339-46. ISSN 1538-7836 |
| Idioma(s) |
en |
| Relação |
http://centaur.reading.ac.uk/44579/ creatorInternal Hughes, C E |
| Tipo |
Article PeerReviewed |
