Thermodynamic and kinetic properties of interpolymer complexes assessed by isothermal titration calorimetry and surface plasmon resonance


Autoria(s): Bizley, Samuel C.; Williams, Adrian C.; Khutoryanskiy, Vitaliy V.
Data(s)

27/08/2014

Resumo

Interpolymer complexes (IPCs) formed between complimentary polymers in solution have shown a wide range of applications from drug delivery to biosensors. This work describes the combined use of isothermal titration calorimetry and surface plasmon resonance to investigate the thermodynamic and kinetic processes during hydrogen-bonded interpolymer complexation. Varied polymers that are commonly used in layer-by-layer coatings and pharmaceutical preparations were selected to span a range of chemical functionalities including some known IPCs previously characterized by other techniques, and other polymer combinations with unknown outcomes. This work is the first to comprehensively detail the thermodynamic and kinetic data of hydrogen bonded IPCs, aiding understanding and detailed characterization of the complexes. The applicability of the two techniques in determining thermodynamic, gravimetric and kinetic properties of IPCs is considered.

Formato

text

Identificador

http://centaur.reading.ac.uk/37783/1/ITC-Biacore-IPC-Soft%20Matter2014.pdf

Bizley, S. C. <http://centaur.reading.ac.uk/view/creators/90005674.html>, Williams, A. C. <http://centaur.reading.ac.uk/view/creators/90000834.html> and Khutoryanskiy, V. V. <http://centaur.reading.ac.uk/view/creators/90000952.html> (2014) Thermodynamic and kinetic properties of interpolymer complexes assessed by isothermal titration calorimetry and surface plasmon resonance. Soft Matter, 10. pp. 8254-8260. ISSN 1744-683X doi: 10.1039/C4SM01138D <http://dx.doi.org/10.1039/C4SM01138D >

Idioma(s)

en

Publicador

Royal Society of Chemistry

Relação

http://centaur.reading.ac.uk/37783/

creatorInternal Bizley, Samuel C.

creatorInternal Williams, Adrian C.

creatorInternal Khutoryanskiy, Vitaliy V.

http://pubs.rsc.org/en/content/articlelanding/2014/sm/c4sm01138d#!divAbstract

10.1039/C4SM01138D

Direitos

cc_by

Tipo

Article

PeerReviewed