Memory versus naive T-cell migration


Autoria(s): Lewis, Marie; Tarlton, John F.; Cose, Stephan
Data(s)

2008

Resumo

Our established understanding of lymphocyte migration suggests that naive and memory T cells travel throughout the body via divergent pathways; naive T cells circulate between blood and lymph whereas memory T cells additionally migrate through non-lymphoid organs. Evidence is now gradually emerging which suggests such disparate pathways between naive and memory T cells may not strictly be true, and that naive T cells gain access to the non-lymphoid environment in numbers approaching that of memory T cells. We discuss here the evidence for naive T-cell traffic into the non-lymphoid environment, compare and contrast this movement with what is known of memory T cells, and finally discuss the functional importance of why naive T cells might access the parenchymal tissues.

Formato

text

Identificador

http://centaur.reading.ac.uk/33298/1/Memory%20versus%20naive%20T-cell%20migration.pdf

Lewis, M. <http://centaur.reading.ac.uk/view/creators/90005327.html>, Tarlton, J. F. and Cose, S. (2008) Memory versus naive T-cell migration. Immunology & Cell biology, 86 (3). pp. 226-231. ISSN 1440-1711 doi: 10.1038/sj.icb.7100132 <http://dx.doi.org/10.1038/sj.icb.7100132>

Idioma(s)

en

Publicador

Nature Publishing Group

Relação

http://centaur.reading.ac.uk/33298/

creatorInternal Lewis, Marie

10.1038/sj.icb.7100132

Tipo

Article

PeerReviewed