Grados altos en la Escala de Fisher predicen el desarrollo de hidrocefalia en pacientes con hemorragia subaracnoidea espontanea


Autoria(s): Herrera-Díaz, Ana-Catalina; Salgado Cardozo, Juan Pablo
Contribuinte(s)

Trillos Peña, Carlos Enrique

Data(s)

08/07/2013

Resumo

Objetive. To determine if high grades of Fisher scale are useful to predict the development of hydrocephalus in consecutive Colombian patients with spontaneous subarachnoid hemorrhage (SAH) assessed from January 2005 to April 2012 with 12 month follow-up. Methods. 251 patients were included in a restrospective manner. The association between Fisher scale and hydrocephalus was analyzed bivariate and multivariate analysis. In addition, a systematic literature review (SLR) was done. Results. In our cohort of patients, the etiology of SAH was due to aneurysms; 78,5%. The prevalence of hydrocephalus was found to be of 27,1%. Overall survival with a 12 month follow-up was of 65,7%. Average age of included patients was 55,5 ± 15 years, and most of them were women; 65,7%. Having Fisher 4 and Hunt-Hess III are significantly associated with hydrocephalus: adjusted OR: 2.93 95% CI: 1.51-5.65, P <0.001, adjusted OR: 2.83 95% CI: 1.31-6.17 P=0.008 respectively. The SRL showed an overall prevalence of hydrocephalus between 17 and 68% and mortality varied between 3.0% and 33%. 50% of the included studies significantly associated intraventricular hemorrhage ( Fisher 4) with hydrocephalus. Conclusion. Our results confirm current concepts on post-SAH hydrocephalus and the fact that is obstructive and secondary to Fisher 4 and having neurological impairment on admission (Hunt and Hess III).

Objetivo: Determinar si los grados altos en la escala de Fisher son útiles como factores pronósticos en el desarrollo de hidrocefalia en pacientes colombianos con diagnóstico de hemorragia subaracnoidea (HSA) espontánea vistos en el Hospital Universitario Clínica San Rafael (HUCSR) desde Enero de 2005 a Abril de 2012 con seguimiento a 12 meses. Métodos: 251 pacientes fueron incluidos en una cohorte restrospectiva. La asociación entre la escala de Fisher y el desarrollo de hidrocefalia en pacientes con HSA espontánea fue analizada a través de un análisis bivariado y multivariado. Se realizó una revisión sistemática de literatura (RSL) enfocada en factores de riesgo asociados con el desarrollo de hidrocefalia en HSA espontánea. Resultados: En nuestra cohorte de pacientes, la etiología de la HSA fue predominantemente por ruptura de aneurismas; 78,5%. La prevalencia de hidrocefalia fue de 27,1%. La sobrevida a 12 meses fue de 65,7%. La edad promedio de los pacientes incluidos fue 55,5 ± 15 años, en su mayoría mujeres 65,7%. Tener Fisher 4 y Hunt-Hess III están asociados con el desarrollo de hidrocefalia: OR ajustado; 2.93 IC 95%: 1.51-5.65, P <0.001, OR ajustado 2.83 IC 95%: 1.31-6.17 P=0.008 respectivamente. La RSL mostró una prevalencia de hidrocefalia de 17 a 68% y una mortalidad entre un 3.0% a 33%. El 50% de los estudios analizados asocian significativamente la hemorragia intraventricular ( Fisher 4) con hidrocefalia. Conclusión: Nuestros resultados confirman conceptos actuales de que la hidrocefalia post HSA es obs-tructiva y secundaria como tener Fisher IV y deterioro neurológico al ingreso (Hunt y Hess III).

Formato

application/pdf

Identificador

http://repository.urosario.edu.co/handle/10336/4515

Idioma(s)

spa

Publicador

Facultad de medicina

Direitos

info:eu-repo/semantics/openAccess

Fonte

reponame:Repositorio Institucional EdocUR

instname:Universidad del Rosario

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Palavras-Chave #ESCALA DE FISHER #ESCALA DE HUNT Y HESS #HEMORRAGIA SUBARACNOIDEA #HIDROCEFALIA #PUNCIÓN ESPINAL #TOMOGRAFÍA COMPUTARIZADA POR RAYOS X #VENTRICULOSTOMÍA #Subarachnoid hemorrhage, Fisher Scale, CT Scan, Hunt-Hess, acute, subacute and chronic hydrocephalus, lumbar puncture, ventriculostomy, ventriculoperitoneal shunt, lamina terminalis fenestration, systematic review of literature.
Tipo

info:eu-repo/semantics/bachelorThesis

info:eu-repo/semantics/acceptedVersion