Efecto del flujo del dializado sobre la ganancia interdialítica en hemodiálisis crónica (Estudio FLUGAIN)


Autoria(s): Guzman Ruiz, Gustavo Adolfo; Yunez Luquetta, Alberto Jose
Contribuinte(s)

Molano Trivino, Alejandra Patricia

Wancjer Meid, Benjamin

Data(s)

23/01/2013

Resumo

Objetivos: Determinar si existe diferencia en la ganancia interdialítica entre los pacientes al ser tratados con flujo de dializado (Qd) de 400 mL/min y 500 mL/min. Diseño: Se realizó un estudio de intervención, cruzado, aleatorizado, doble ciego en pacientes con enfermedad renal crónica en hemodiálisis para determinar diferencias en la ganancia de peso interdialítica entre los pacientes tratados con flujo de dializado (Qd) de 400 ml/min y 500 ml/min. Pacientes: Se analizaron datos de 46 pacientes en hemodiálisis crónica con Qd de 400 ml/min y 45 con Qd de 500 ml/min. Análisis: La prueba de hipótesis para evaluar diferencias en la ganancia interdialítica y las otras variables entre los grupos se realizó mediante la prueba T para muestras pareadas. Para el análisis de correlación se calculó el coeficiente de Pearson. Resultados: No hubo diferencia significativa en ganancia interdialítica usando Qd de 400 ml/min vs 500 ml/min (2.37 ± 0.7 vs 2.41 ± 0.6, p=0.41) ni en Kt/V (1.57 ± 0.25 vs 1.59 ± 0.23, p = 0.45), potasio (4.9 ± 1.1 vs 5.1 ± 1.0, p=0.45), fosforo (4.5 ± 1.2 vs 4.4 ± 1.2, p=0.56) o hemoglobina (11.3 ± 1.8 vs 11.3 ± 1.6, p=0.96). Conclusiones: En pacientes con peso ≤ 65 Kg el uso de Qd de 400 ml/min no se asocia con menor ganancia interdialítica de peso. No hay diferencia en la eficiencia de diálisis lo que sugiere que es una intervención segura a corto plazo.

RTS-Agencia Cardioinfantil

Objective: To determine if there is a difference in interdialytic weight gain between patients treated with dialysate flow (Qd) of 400 mL / min vs Qd of 500 mL / min. Design: We conducted an intervention, crossover, randomized, double-blind study in patients with chronic kidney disease on hemodialysis to determine differences in interdialytic weight gain in patients treated with dialysate flow (Qd) of 400 ml / min and 500 ml / min. Patients: We analyzed data from 46 patients on chronic hemodialysis with Qd 400 ml / min and 45 with Qd 500 ml / min. Analysis: : Hypothesis testing for differences in interdialytic weight gain and other variables between groups was performed by paired t test. For the correlation analysis we calculated the Pearson coefficient. Results: There was no significant difference in interdialytic weight gain using QD 400 ml / min vs 500 ml / min (2.37 ± 0.7 vs 2.41 ± 0.6, p = 0.41) nor in Kt / V (1.57 ± 0.25 vs 1.59 ± 0.23, p = 0.45), potassium (4.9 ± 1.1 vs 5.1 ± 1.0, p = 0.45), phosphorus (4.5 ± 1.2 vs 4.4 ± 1.2, p = 0.56) or hemoglobin (11.3 ± 1.8 vs 11.3 ± 1.6, p = 0.96). Conclusions : In patients weighing ≤ 65 kg QD using 400 ml / min is not associated with lower interdialytic weight gain. We found no difference in dialysis efficiency which suggests that lowering Qd is a safe intervention at short term.

Formato

application/pdf

Identificador

http://repository.urosario.edu.co/handle/10336/4156

Idioma(s)

spa

Publicador

Facultad de Medicina

Direitos

info:eu-repo/semantics/openAccess

Fonte

reponame:Repositorio Institucional EdocUR

instname:Universidad del Rosario

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TEME 0003 2013

Palavras-Chave #ENFERMEDADES CARDIOVASCULARES - TRATAMIENTO #ENFERMEDADES RENALES - TRATAMIENTO #HEMODIALISIS - UTILIZACIÓN #NEFROLOGÍA - INVESTIGACIONES #Dialysate flow #interdialytic weight gain #hemodialysis
Tipo

info:eu-repo/semantics/bachelorThesis

info:eu-repo/semantics/acceptedVersion