Hemodynamic changes during posterior epilepsies: an eeg-fnirs study
Data(s) |
22/03/2015
22/03/2015
2014
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Resumo |
Posterior epilepsies are relatively rare, mainly suspected clinically by the presence of visual auras. Functional near-infrared spectroscopy (fNIRS) is an emerging non-invasive imaging technique that has the potential to monitor hemodynamic changes during epileptic activity. Combined with electroencephalography (EEG), 9 patients with posterior epilepsies were recorded using EEG-fNIRS with large sampling (19 EEG electrodes and over 100 fNIRS channels). Spikes and seizures were carefully marked on EEG traces, and convolved with a standard hemodynamic response function for general linear model (GLM) analysis. GLM results for seizures (in 3 patients) and spikes (7 patients) were broadly sensitive to the epileptic focus in 7/9 patients, and specific in 5/9 patients with fNIRS deoxyhemoglobin responses lateralized to the correct lobe, and to plausible locations within the occipital or parietal lobes. This work provides evidence that EEG-fNIRS is a sensitive technique for monitoring posterior epileptic activity. CIHR (282447), FRSQ (14385), CIHR-HSF (203422) |
Identificador |
Pouliot P., Tran TPY, Birca V., Vannasing P., Tremblay J., Lassonde M., Nguyen DK. Hemodynamic changes during posterior epilepsies: an EEG-fNIRS study. Epilepsy Research 2014; 108(5):883-890. doi:10.1016/j.eplepsyres.2014.03.007 |
Idioma(s) |
en |
Publicador |
Elsevier |
Palavras-Chave | #EEG-fNIRS #Hemodynamic response #Epileptic spikes #Seizures #Occipital lobe epilepsy #Crises épileptiques #Épilepsies partielles |
Tipo |
Article |