14-3-3 proteins in apoptosis
| Data(s) |
01/04/2003
|
|---|---|
| Resumo |
The once obscure members of the 14-3-3 protein family play significant roles in the determination of cell fate. By inhibiting the pro-apoptotic BAD (Bcl-2-antagonist of cell death) and the transcription factor FKHRL-1, 14-3-3 displays important anti-apoptotic characteristics. To date, five points of interaction of 14-3-3 with the apoptotic machinery have been identified. How these interactions are regulated still remains a mystery. |
| Formato |
text/html |
| Identificador |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000400001 |
| Idioma(s) |
en |
| Publicador |
Associação Brasileira de Divulgação Científica |
| Fonte |
Brazilian Journal of Medical and Biological Research v.36 n.4 2003 |
| Palavras-Chave | #14-3-3 #Apoptosis #Programmed cell death |
| Tipo |
journal article |
