Immunohistochemical expression of HER-2/NEU-CERBB-2 in patients with adenocarcinoma of the stomach


Autoria(s): Cirne-Lima,Fernando K; Rosa,Aline de Souza; Kulczynski,Jane M U; Mattana,Diego S; Corezolla,Kizzy; Moreira,Luis F
Data(s)

01/04/2009

Resumo

OBJECTIVES: To determine the prevalence of Her-2/Neu-cerbb-2 in the gastric mucosa of patients with gastric adenocarcinoma in a brazilian patient group. METHODS: The immunohistochemical expression of Her-2/Neu was studied in 37 formalin-fixed paraffin-embedded tissue sections. RESULTS: The immunohistochemical reaction produced by the anti-HER-2/Neu antibody was positive in two cases (5.4%). CONCLUSION: The low prevalence of Her-2/Neu observed in these southern brazilian cases is probably due to the great number of poorly differentiated cancers in this serie.

Formato

text/html

Identificador

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912009000200007

Idioma(s)

en

Publicador

Colégio Brasileiro de Cirurgiões

Fonte

Revista do Colégio Brasileiro de Cirurgiões v.36 n.2 2009

Palavras-Chave #Stomach neoplasms #Oncogenes #Immunohistochemistry
Tipo

journal article