Spot-test identification and rapid quantitative sequential analysis of dipyrone


Autoria(s): Tubino,M.; Biondo,A. C.; Vila,M. M. D. C.; Pezza,L.; Pezza,H. R.
Data(s)

01/01/2010

Resumo

A qualitative spot-test and tandem quantitative analysis of dipyrone in the bulk drug and in pharmaceutical preparations is proposed. The formation of a reddish-violet color indicates a positive result. In sequence a quantitative procedure can be performed in the same flask. The quantitative results obtained were statistically compared with those obtained with the method indicated by the Brazilian Pharmacopoeia, using the Student's t and the F tests. Considering the concentration in a 100 µL aliquot, the qualitative visual limit of detection is about 5×10-6 g; instrumental LOD ≅ 1.4×10-4 mol L-1 ; LOQ ≅ 4.5×10-4 mol L-1.

Formato

text/html

Identificador

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702010000100005

Idioma(s)

en

Publicador

Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP

Fonte

Eclética Química v.35 n.1 2010

Palavras-Chave #dipyrone #spot-test #analysis #qualitative #quantitative
Tipo

journal article