Interaction study of moxifloxacin with Cu(II) ion using square-wave voltammetry and its application in the determination in tablets
Data(s) |
01/01/2006
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Resumo |
This work presents an electroanalytical method for the determination of moxifloxacin (MOXI) in tablets by its interaction with Cu(II) ion and subsequent electrochemical reduction at hanging mercury drop electrode (HMDE). A well-defined reduction peak at -0.21 V vs. Ag/AgCl in Phosphate buffer 0.04 mol L-1 pH 8.0 was observed for the complex reduction MOXI-Cu(II), using square-wave voltammetry (SWV). Using a 10 s of accumulation time at -0.40 V was found a limit detection of 3.60x10-8 mol l-1. The obtained results have shown good agreement with those obtained by spectrophotometric method. |
Formato |
text/html |
Identificador |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702006000100004 |
Idioma(s) |
en |
Publicador |
Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP |
Fonte |
Eclética Química v.31 n.1 2006 |
Palavras-Chave | #moxifloxacin #electroanalysis #complexation of moxifloxacin |
Tipo |
journal article |