Interaction study of moxifloxacin with Cu(II) ion using square-wave voltammetry and its application in the determination in tablets


Autoria(s): Trindade,M. A. G.; Cunha,P. A. C.; Araújo,T. A. de; Silva,G. M. da; Ferreira,V. S.
Data(s)

01/01/2006

Resumo

This work presents an electroanalytical method for the determination of moxifloxacin (MOXI) in tablets by its interaction with Cu(II) ion and subsequent electrochemical reduction at hanging mercury drop electrode (HMDE). A well-defined reduction peak at -0.21 V vs. Ag/AgCl in Phosphate buffer 0.04 mol L-1 pH 8.0 was observed for the complex reduction MOXI-Cu(II), using square-wave voltammetry (SWV). Using a 10 s of accumulation time at -0.40 V was found a limit detection of 3.60x10-8 mol l-1. The obtained results have shown good agreement with those obtained by spectrophotometric method.

Formato

text/html

Identificador

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702006000100004

Idioma(s)

en

Publicador

Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP

Fonte

Eclética Química v.31 n.1 2006

Palavras-Chave #moxifloxacin #electroanalysis #complexation of moxifloxacin
Tipo

journal article