Estudo químico e atividades antiproliferativa, tripanocida e leishmanicida de Maxillaria picta


Autoria(s): Almeida,Thiago L. de; Monteiro,Josiane A.; Lopes,Greice K. P.; Chiavelli,Lucas U. R.; Santin,Silvana M. de O.; Silva,Cleuza C. da; Kaplum,Vanessa; Scariot,Débora B.; Nakamura,Celso V.; Ruiz,Ana L. T. G.; Carvalho,João E.; Faria,Ricardo T. de; Pomini,Armando M.
Data(s)

01/01/2014

Resumo

The chemical study of the orchid Maxillaria picta resulted in the isolation of the bioactive stilbenes phoyunbene B and phoyunbene C, in addition to four phenolic acids, one xanthone, steroidal compounds and two triterpenes. Crude extract, fractions, subfractions and the isolated xanthone were evaluated for anticancer activity against human tumor cell lines and against evolutionary forms of T. cruzi and L. amazonensis. The structures of the compounds were determined by GC-MS, and ¹H NMR, 13C NMR spectral methods as well as bidimensional techniques.

Formato

text/html

Identificador

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000700008

Idioma(s)

pt

Publicador

Sociedade Brasileira de Química

Fonte

Química Nova v.37 n.7 2014

Palavras-Chave #Maxillaria #Trypanosoma #Leishmania #stilbenes
Tipo

journal article