Análise térmica aplicada a fármacos e formulações farmacêuticas na indústria farmacêutica


Autoria(s): Oliveira,Marcelo Antonio de; Yoshida,Maria Irene; Lima Gomes,Elionai Cassiana de
Data(s)

01/01/2011

Resumo

Several matters of the pharmaceutical demonstrate the great importance of thermal analysis application, especially TG and DSC for the pharmaceutical industry future, namely: characterization of the drugs with the thermal events definition, in studies of drug purity, in the polymorphs identification, in compatibility studies of solid dosage pharmaceutical formulations, in drugs and pharmaceutical formulations thermal stability, and in determination of shelf life for isothermal degradation kinetics by extrapolation using the Arrhenius equation. Thus, the test results obtained from thermal analysis are directly related to the quality of a pharmaceutical product, whether the stability or bioavailability of the pharmaceutical product.

Formato

text/html

Identificador

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000700022

Idioma(s)

pt

Publicador

Sociedade Brasileira de Química

Fonte

Química Nova v.34 n.7 2011

Palavras-Chave #thermal analysis #pharmaceutical industry #characterization
Tipo

journal article