Flow analysis-hydride generation-gas phase derivative molecular absorption spectrophotometric determination of antimony in antileishmanial drugs


Autoria(s): Gallignani,Máximo; Brunetto,María del Rosario; Ovalles,Fernando
Data(s)

01/01/2009

Resumo

In the present work, the development of a method based on the coupling of flow analysis (FA), hydride generation (HG), and derivative molecular absorption spectrophotometry (D-EAM) in gas phase (GP), is described in order to determine total antimony in antileishmanial products. Second derivative order (D²224nm) of the absorption spectrum (190 - 300 nm) is utilized as measurement criterion. Each one of the parameters involved in the development of the proposed method was examined and optimized. The utilization of the EAM in GP as detection system in a continuous mode instead of atomic absorption spectrometry represents the great potential of the analytic proposal.

Formato

text/html

Identificador

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000200013

Idioma(s)

en

Publicador

Sociedade Brasileira de Química

Fonte

Química Nova v.32 n.2 2009

Palavras-Chave #gaseous phase UV molecular absorption spectrophotometry #antimony #leishmaniasis
Tipo

journal article