Estudo comparativo de técnicas de screening para avaliação da atividade anti-bacteriana de extratos brutos de espécies vegetais e de substâncias puras


Autoria(s): Alves,Everton Giovanni; Vinholis,Adriana Helena Chicharo; Casemiro,Luciana Assirati; Furtado,Niege Araçari Jacometti Cardoso; Silva,Márcio Luis Andrade e; Cunha,Wilson Roberto; Martins,Carlos Henrique Gomes
Data(s)

01/01/2008

Resumo

In this work, the effectiveness of four screening techniques (three techniques of the diffusion method and one microdilution broth method) were compared. Evaluated were the ethanolic and dichloromethanic extracts of Miconia rubiginosa (Melastomataceae) against six standard bacteria (ATCC). The results showed statistical disagreement among the three diffusion techniques. Among the diffusion techniques, the well technique displayed the best result. However the microdilution broth method demonstrated to be the most adequate method to evaluate the antibacterial activity of plant crude extracts and pure compounds when compared to the other methodologies.

Formato

text/html

Identificador

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000500052

Idioma(s)

pt

Publicador

Sociedade Brasileira de Química

Fonte

Química Nova v.31 n.5 2008

Palavras-Chave #antimicrobial activity #screening methods #plant extracts
Tipo

journal article