Síntese de 1-indanonas através da reação de acilação de Friedel-Crafts intramolecular utilizando NbCl5 como ácido de Lewis
| Data(s) |
01/01/2008
|
|---|---|
| Resumo |
The intramolecular Friedel-Crafts acylation reaction of 3-arylpropanoic acids to give 1-indanones can be effected in good yields under mild conditions (room temperature) by using niobium pentachloride. Our results indicate that NbCl5 acts both as reagent (to transform carboxylic acids into acyl chlorides) and as catalyst in the Friedel-Crafts cyclization. |
| Formato |
text/html |
| Identificador |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000400010 |
| Idioma(s) |
pt |
| Publicador |
Sociedade Brasileira de Química |
| Fonte |
Química Nova v.31 n.4 2008 |
| Palavras-Chave | #intramolecular Friedel-Crafts acylation reaction #niobium pentachloride #synthesis of 1-indanones |
| Tipo |
journal article |
